RejuviRxImportant Safety Information
Read this information before starting any GLP-1 medication and discuss it with your licensed provider. Last updated October 29, 2026.
About Compounded Medications
Compounded semaglutide and compounded tirzepatide are prepared by licensed pharmacies for individual patients based on a valid prescription. Compounded medications are not FDA-approved, and the FDA does not review them for safety, effectiveness, or quality. They are not the same as, and are not substitutes for, any brand-name product.
Risk of Thyroid C-Cell Tumors
In studies in rodents, semaglutide and tirzepatide caused thyroid C-cell tumors. It is unknown whether they cause such tumors, including medullary thyroid carcinoma (MTC), in humans. Do not use these medications if you or a family member have ever had MTC or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Tell your provider if you develop a lump or swelling in the neck, trouble swallowing, hoarseness, or shortness of breath.
Do Not Use If
You have a personal or family history of MTC or MEN 2, have had a serious allergic reaction to the active ingredient, or are pregnant, planning to become pregnant, or breastfeeding.
Possible Serious Side Effects
Inflammation of the pancreas (pancreatitis), gallbladder problems, low blood sugar (especially with insulin or sulfonylureas), kidney problems including dehydration-related kidney injury, serious allergic reactions, changes in vision in people with diabetes, increased heart rate, and depression or thoughts of self-harm. Stop use and seek medical help right away if you have severe stomach pain that will not go away, signs of an allergic reaction, or other severe symptoms.
Common Side Effects
Nausea, vomiting, diarrhea, constipation, abdominal pain, indigestion, decreased appetite, fatigue, and injection-site reactions.
Before Starting
Tell your provider about all medical conditions and all medications you take, including prescription, over-the-counter, vitamins, and supplements. These medications slow stomach emptying and may affect how other oral medications, including oral birth control, are absorbed.
Reporting Side Effects
Contact your provider about any side effects. You may also report side effects to the FDA MedWatch program at www.fda.gov/medwatch or 1-800-FDA-1088.